The two sides last met in December when a late Angelo Ogbonna strike sealed all three points for the Hammers after Tomas Soucek has equalised.
With ‘keeper jeopardy and attacking options aplenty, we’ve picked the side we believe Moyes will pick…
GK - Lukasz Fabianski
Missed the Manchester City defeat with an arm problem and hadn’t trained during the week.
Should he recover in time and the Pole is a must.
RB - Vladimir Coufal
Visibly disappointed to lose last week and will be one of many determined to get back to winning ways.
CB - Craig Dawson
Has been nothing short of outstanding since getting his chance and has taken over as leader of the defence.
CB - Issa Diop
Equipped himself well since coming in for the injured Angelo Ogbonna.
Tough test against a fluid Leeds side but can stake his long-term claim once more.
LB - Aaron Cresswell
Mr. Consistent once again this season and continues to stave off the belief a replacement is required.
Will have his hands full against Raphinha but more than capable of hurting Leeds as well.
CM - Declan Rice
Another big night on the captain’s hands alongside Soucek.
Played every minute of the season but the lure of European football will drive him over the line.
CM - Tomas Soucek
Quiet by his previous high standards in recent weeks
No better time to return to form for the run-in.
RW - Jarrod Bowen
Hasn’t scored the goals he would’ve liked recently but his running and industry make the former Hull man a must pick.
CAM - Jesse Lingard
Undroppable having made a superb start to life as an Iron.
LW - Pablo Fornals
The Spaniard’s industry and work rate will be imperative as West Ham look to contain an interchanging Leeds side whilst having their own impact.
CF - Michail Antonio
Another goal last weekend for the talisman who continues to deliver.
May not be at his peak fitness but his presence is so important.